This is an ultra high performance 500 S&W loading. It is safe to use in any and all 500 S&W chambered firearms except guns that are fed from magazine tubes. Always use flat nose bullets in guns fed from magazine tubes. This spire pointed all copper Barnes XPB bullet will fly very flat and penetrate very deep for an expanding bullet. This load can be used on animals as large as Bison or Cape buffalo. For an expanding load has a super high velocity and penetrates deep.